Priorities in Pharmaceutical Research

Research priorities in bronchiectasis.

Taking a network approach, we have identified research priorities in non-cystic fibrosis bronchiectasis. We discuss these in the context of increasing recognition of bronchiectasis and increasing mortality rates.

Research priorities in traditional Chinese

Biomarkers in Pharmaceutical Research.

BACKGROUND Biomarkers are important tools in drug development and are used throughout pharmaceutical research. CONTENT This review focuses on molecular biomarkers in drug development. It contains sections on how biomarkers are used to assess target engagement, pharmacodynamics, safety, and proof-of-concept. It also covers the use of biomarkers as surrogate end points and patient selection/com...

Priorities of ophthalmic research.

The purpose of research is to uncover truths, that is to describe reality validly. But all truths are not equally generalizable, and all research is not equally justifiable. For example, the value of a study that requires an N of 100,000 to reach statistical significance (a presumed truth) is likely to be far less than that of a study requiring only an N of 10. Furthermore, the value of researc...

Research priorities are critical.

Building on the review by Goldner et al., I argue that the first research tasks for disability management in Canada should be to articulate conceptual models; define promising disability management interventions and characterize the current longitudinal health and labour market trajectories of Canadians disabled by mental conditions. Research should next emphasize pilot studies of novel interve...